I am interested in cancer and the dynamics of evolution and differentiation trajectories, and use genomic and epigenomic data, experimental evolution, and models to explore related questions.
I lead a group in Oncology Data Science at Novartis Institutes for BioMedical Research, and previously worked with Andreas Wagner at the University of Zurich and Paul Sniegowski at the University of Pennsylvania looking at the genomic consequences of very high mutation rates. I obtained my PhD from the Genomics and Computational Biology program at the University of Pennsylvania with Carlo Maley. There, I explored the dynamics of asexual evolution and differentiation architecture in cancer cell populations.
Before embarking on my academic trajectory, I wrote software and databases. My undergraduate studies at Reed College were in Biochemistry and Molecular Biology, and I studied Computer and Information Technology at the University of Pennsylvania.
You can find my publications on Google Scholar.